SGC8158
Product Specifications
Target
Histone Methyltransferase
Related Pathways
Chromatin/Epigenetic
Bioactivity
SGC8158 is an inhibitor of PRMT7 and is useful for studying the cellular function of PRMT7. It reduces the monomethyl arginine levels of Hsp70 (a common substrate of PRMT7) . SGC8158 can inhibit the growth of various cancer cells (IC50: 2-9 μM) and multidrug-resistant (MDR) cancer cells, and it also enhances the DNA damage and cytotoxicity induced by Doxorubicin.
Molecular Formula
C27H31ClN6O3S
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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