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HDAC6-IN-44

Product Specifications

Target

HDAC

Related Pathways

Chromatin/Epigenetic, DNA Damage/DNA Repair

Bioactivity

HDAC6-IN-44 (compound H10) is a selective HDAC6 inhibitor with an IC50 value of 8.97 nM. It can suppress idiopathic pulmonary fibrosis phenotypes and exhibits anti-fibrotic activity in the lungs. Additionally, HDAC6-IN-44 has been shown to inhibit fibrosis progression in a bleomycin-induced mouse model and demonstrates good metabolic stability, making it a promising candidate for idiopathic pulmonary fibrosis research.

Molecular Formula

C20H21N3O3

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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