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SGK1-IN-3 hydrochloride

Product Specifications

Target

SGK

Related Pathways

Metabolism

Bioactivity

SGK1-IN-3 hydrochloride (compound 3a) is an efficacious, orally bioavailable SGK1 inhibitor. The serine/threonine kinase SGK1 acts as an activator of the ?-catenin pathway and strongly stimulates cartilage degradation, being upregulated under genomic control in diseased osteoarthritic cartilage. SGK1-IN-3 hydrochloride holds potential for osteoarthritis research.

Molecular Formula

C23H21Cl3N6O3S

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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