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Paclitaxel-2′-succinate NHS ester

Product Specifications

CAS Number

245110-80-9

Target

Microtubule Associated

Related Pathways

Cytoskeletal Signaling

Bioactivity

Paclitaxel-2′-succinate NHS ester is a derivative of paclitaxel featuring a succinate linker with its carboxyl group activated as an NHS ester. The NHS ester moiety exhibits high reactivity towards amino or hydroxyl groups, facilitating its conjugation with various molecules (such as peptides, proteins, antibodies, enzymes, or polymers) . This compound is utilized in the development of nanomedicines and cancer research.

Smiles

O(C(C)=O)[C@]12[C@]3([C@H](OC(=O)C4=CC=CC=C4)[C@@]5(O)C(C)(C)C([C@@H](OC(C)=O)C(=O)[C@]3(C)[C@@H](O)C[C@]1(OC2)[H])=C(C)[C@@H](OC([C@@H]([C@@H](NC(=O)C6=CC=CC=C6)C7=CC=CC=C7)OC(CCC(ON8C(=O)CCC8=O)=O)=O)=O)C5)[H]

Molecular Formula

C55H58N2O19

Molecular Weight

1051.05

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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