Paclitaxel-2?-succinate NHS ester
Product Specifications
CAS Number
245110-80-9
Target
Microtubule Associated
Related Pathways
Cytoskeletal Signaling
Bioactivity
Paclitaxel-2?-succinate NHS ester is a derivative of paclitaxel featuring a succinate linker with its carboxyl group activated as an NHS ester. The NHS ester moiety exhibits high reactivity towards amino or hydroxyl groups, facilitating its conjugation with various molecules (such as peptides, proteins, antibodies, enzymes, or polymers) . This compound is utilized in the development of nanomedicines and cancer research.
Smiles
O(C(C)=O)[C@]12[C@]3([C@H](OC(=O)C4=CC=CC=C4)[C@@]5(O)C(C)(C)C([C@@H](OC(C)=O)C(=O)[C@]3(C)[C@@H](O)C[C@]1(OC2)[H])=C(C)[C@@H](OC([C@@H]([C@@H](NC(=O)C6=CC=CC=C6)C7=CC=CC=C7)OC(CCC(ON8C(=O)CCC8=O)=O)=O)=O)C5)[H]
Molecular Formula
C55H58N2O19
Molecular Weight
1051.05
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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