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PF-06442609

Product Specifications

Target

Gamma-secretase

Related Pathways

Neuroscience|||Stem Cells|||Proteases/Proteasome

Bioactivity

PF-06442609 is an orally active ?-secretase modulator with an IC50 value of 6 nM for A?42. It exhibits good CNS permeability.

Smiles

O=C1N2C(C(=O)N([C@H](COC3=C([C@H](C(F)(F)F)C)C=C(F)C=C3)C)CC2)=CC=C1N4C=NC(C)=C4

Molecular Formula

C24H24F4N4O3

Molecular Weight

492.47

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Product Datasheet

https://www.targetmol.com/attachment/DataSheet/372420802911404178/T210322

CAS Number

1402002-76-9

Available Sizes

Curated Selection

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