PF-06442609
Product Specifications
CAS Number
1402002-76-9
Target
Gamma-secretase
Related Pathways
Neuroscience, Stem Cells, Proteases/Proteasome
Bioactivity
PF-06442609 is an orally active γ-secretase modulator with an IC50 value of 6 nM for Aβ42. It exhibits good CNS permeability.
Smiles
O=C1N2C(C(=O)N([C@H](COC3=C([C@H](C(F)(F)F)C)C=C(F)C=C3)C)CC2)=CC=C1N4C=NC(C)=C4
Molecular Formula
C24H24F4N4O3
Molecular Weight
492.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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