PF-06442609

1402002-76-9

Gamma-secretase

Neuroscience|||Stem Cells|||Proteases/Proteasome

PF-06442609 is an orally active ?-secretase modulator with an IC50 value of 6 nM for A?42. It exhibits good CNS permeability.

O=C1N2C(C(=O)N([C@H](COC3=C([C@H](C(F)(F)F)C)C=C(F)C=C3)C)CC2)=CC=C1N4C=NC(C)=C4

C24H24F4N4O3

492.47

Cool pack

-20°C

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