CDK4/6-IN-15 hydrochloride
Product Specifications
Target
CDK
Related Pathways
Cell Cycle/Checkpoint
Bioactivity
CDK4/6-IN-15 hydrochloride is an orally active selective inhibitor of CDK4/6. It effectively restrains the growth of cancer cells by arresting the cell cycle at the G1 phase. Additionally, CDK4/6-IN-15 hydrochloride inhibits phosphorylation of the retinoblastoma tumor suppressor protein (Rb) at site S780 and suppresses E2 factor (E2F) -regulated gene expression.
Molecular Formula
C21H28ClFN8S
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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