PROTAC JAK1 degrader 1
Product Specifications
CAS Number
3052553-20-2
Target
PROTACs
Related Pathways
PROTAC
Bioactivity
PROTACJAK1 degrader 1 (compound 10c) is a potent and selective PROTAC JAK1 degrader with a DC50 of 214 nM. It also exhibits antitumor activity.
Smiles
N#CCNC(=O)C=1C=CC(=CC1)C2=NC(=NC=C2)NC3=CC=C(C=C3)N4CCC(C(=O)NCCCCC#CC5=CC=CC=6C(=O)N(C(=O)C56)C7C(=O)NC(=O)CC7)CC4
Molecular Formula
C44H41N9O6
Molecular Weight
791.85
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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