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PROTAC JAK1 degrader 1

Product Specifications

CAS Number

3052553-20-2

Target

PROTACs

Related Pathways

PROTAC

Bioactivity

PROTACJAK1 degrader 1 (compound 10c) is a potent and selective PROTAC JAK1 degrader with a DC50 of 214 nM. It also exhibits antitumor activity.

Smiles

N#CCNC(=O)C=1C=CC(=CC1)C2=NC(=NC=C2)NC3=CC=C(C=C3)N4CCC(C(=O)NCCCCC#CC5=CC=CC=6C(=O)N(C(=O)C56)C7C(=O)NC(=O)CC7)CC4

Molecular Formula

C44H41N9O6

Molecular Weight

791.85

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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