What is the catalog number for FXIIa-IN-5?

The catalog number for FXIIa-IN-5 is T210261.

What sizes are available for FXIIa-IN-5?

FXIIa-IN-5 is available in the following size(s): 10 mg, 50 mg.

How many pack sizes does FXIIa-IN-5 come in?

FXIIa-IN-5 is available in 2 different pack sizes.

Is FXIIa-IN-5 in stock?

FXIIa-IN-5 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures FXIIa-IN-5?

FXIIa-IN-5 is manufactured by Molfinity.

What is the estimated delivery time for FXIIa-IN-5?

Estimated delivery time for FXIIa-IN-5 is approximately 10 business day(s), depending on your location.

FXIIa-IN-5

Product Specifications

CAS Number

3047411-80-0

Target

Thrombin

Related Pathways

Proteases/Proteasome

Bioactivity

FXIIa-IN-5 (Compound 4J) is an orally effective selective inhibitor of factor XIIa (FXIIa), with an IC50 of 21 nM. It inhibits the intrinsic coagulation pathway and demonstrates anti-inflammatory and antithrombotic activities in a Carrageenan-induced thrombosis model in mice. FXIIa-IN-5 exhibits moderate pharmacokinetic properties and mild toxicity at a dosage of 100 mg/kg.