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ARM165

Product Specifications

Target

PROTACs, Akt, PI3K

Related Pathways

Cytoskeletal Signaling, PI3K/Akt/mTOR signaling, PROTAC

Bioactivity

ARM165 is a heterobifunctional molecule that degrades the protein PIK3CG and inhibits the PI3Kγ-Akt signaling pathway, thereby exerting anti-leukemic effects. It is capable of suppressing the proliferation of AML cells, with an IC50 of less than 1 μM.

Molecular Formula

C44H51N7O8S

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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