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NLRP3-IN-42

Product Specifications

Target

NOD-like Receptor (NLR), Interleukin

Related Pathways

Immunology/Inflammation

Bioactivity

NLRP3-IN-42 (compound H28) is a potent inhibitor of NLRP3 with a KD value of 1.15 μM. It effectively reduces the protein expression of cleaved-caspase-1 (p20) induced by LPS and selectively inhibits the release of IL-1β.

Molecular Formula

C29H27F3N2O3S2

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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