D-01
Product Specifications
Target
Histone Methyltransferase, HIF/HIF Prolyl-Hydroxylase
Related Pathways
Metabolism, Chromatin/Epigenetic
Bioactivity
D-01 is a dual-target inhibitor of HIF-1α and EZH2, with IC50 values of 4.86 μM and 0.99 μM, respectively. It suppresses the expression of the H3K27me3 protein and inhibits the migration, colony formation, and invasion of A549 cells, as well as lumen formation in HUVEC. D-01 is applicable in lung cancer research.
Molecular Formula
C37H43N3O8
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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