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D-01

Product Specifications

Target

Histone Methyltransferase, HIF/HIF Prolyl-Hydroxylase

Related Pathways

Metabolism, Chromatin/Epigenetic

Bioactivity

D-01 is a dual-target inhibitor of HIF-1α and EZH2, with IC50 values of 4.86 μM and 0.99 μM, respectively. It suppresses the expression of the H3K27me3 protein and inhibits the migration, colony formation, and invasion of A549 cells, as well as lumen formation in HUVEC. D-01 is applicable in lung cancer research.

Molecular Formula

C37H43N3O8

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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