LLW-018
Product Specifications
CAS Number
3049369-11-8
Target
PD-1/PD-L1
Related Pathways
Apoptosis, Cell Cycle/Checkpoint, Immunology/Inflammation
Bioactivity
LLW-018 is a potent PD-1/PD-L1 inhibitor with an IC50 value of 2.61 nM. It can disrupt the PD-1/PD-L1 interaction, with a cell-based PD-1/PD-L1 blocking bioassay IC50 value of 0.88 μM. LLW-018 holds potential for research in immune-related diseases.
Smiles
ClC1=CC(=CC=C1OCC=2C=CC=C(C=3C=CC=C4C(=NSC43)NC5=CC=C(C=C5Cl)CNC(CO)CO)C2C)CNC(CO)CO
Molecular Formula
C35H38Cl2N4O5S
Molecular Weight
697.67
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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