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LLW-018

Product Specifications

CAS Number

3049369-11-8

Target

PD-1/PD-L1

Related Pathways

Apoptosis|||Cell Cycle/Checkpoint|||Immunology/Inflammation

Bioactivity

LLW-018 is a potent PD-1/PD-L1 inhibitor with an IC50 value of 2.61 nM. It can disrupt the PD-1/PD-L1 interaction, with a cell-based PD-1/PD-L1 blocking bioassay IC50 value of 0.88 ?M. LLW-018 holds potential for research in immune-related diseases.

Smiles

ClC1=CC(=CC=C1OCC=2C=CC=C(C=3C=CC=C4C(=NSC43)NC5=CC=C(C=C5Cl)CNC(CO)CO)C2C)CNC(CO)CO

Molecular Formula

C35H38Cl2N4O5S

Molecular Weight

697.67

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Product Datasheet

https://www.targetmol.com/attachment/DataSheet/372420802911404033/T210223

Available Sizes

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