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PI3K?-IN-22

Product Specifications

Target

PI3K

Related Pathways

PI3K/Akt/mTOR signaling

Bioactivity

PI3K?-IN-22 (Compound 26) is a selective inhibitor of PI3K? with a pKi value of 9.3. It effectively inhibits the PI3K?-AKT signaling pathway in THP-1 cells, demonstrating a pIC50 of 9.4. Additionally, PI3K?-IN-22 exhibits favorable pharmacokinetic properties in rats.

Molecular Formula

C27H35FN8O4S

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Product Datasheet

https://www.targetmol.com/attachment/DataSheet/372420802907209956/T210218

Available Sizes

Curated Selection

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