BuChE-IN-11
Product Specifications
Target
Cholinesterase (ChE)
Related Pathways
Neuroscience
Bioactivity
BuChE-IN-11 (Compound 3b-1) is a selective inhibitor of BuChE with an IC50 of 0.44 ?M for hBuChE. The compound demonstrates high brain-blood barrier permeability and possesses free radical scavenging capabilities, indicating significant antioxidant activity. BuChE-IN-11 interacts with the choline binding site, the acyl binding site, and the peripheral anionic site, showing submicromolar inhibitory activity against BuChE and preventing the self-aggregation of ?-amyloid protein (A?) . This compound holds promise for research in the field of Alzheimer's disease.
Molecular Formula
C28H27FN4O2
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Product Datasheet
https://www.targetmol.com/attachment/DataSheet/372420802907209950/T210214
Available Sizes
Curated Selection
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