TLR7 agonist 22
Product Specifications
Target
TLR
Related Pathways
Immunology/Inflammation
Bioactivity
TLR7 agonist22 (Compound 11a) is a selective TLR7 agonist with an IC50 value of 25.86 ?M. It inhibits the secretion of cell HBsAg and effectively activates TLR7, inducing the release of TLR7-regulated cytokines IL-12, TNF-?, and IFN-? in human PBMC cells. TLR7 agonist22 shows promise for developing novel immunomodulatory drugs in HBV research.
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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