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TLR7 agonist 22

Product Specifications

Target

TLR

Related Pathways

Immunology/Inflammation

Bioactivity

TLR7 agonist22 (Compound 11a) is a selective TLR7 agonist with an IC50 value of 25.86 ?M. It inhibits the secretion of cell HBsAg and effectively activates TLR7, inducing the release of TLR7-regulated cytokines IL-12, TNF-?, and IFN-? in human PBMC cells. TLR7 agonist22 shows promise for developing novel immunomodulatory drugs in HBV research.

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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