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PROTAC PD-L1 degrader-1

Product Specifications

Target

PD-1/PD-L1, PROTACs

Related Pathways

PROTAC, Apoptosis, Immunology/Inflammation, Cell Cycle/Checkpoint

Bioactivity

PROTACPD-L1 degrader-1 is a CRBN-based PD-L1-PROTAC degrader with significant PD-L1 protein degradation capacity. It demonstrates strong PD-L1 degradation activity in 4T1 cells, with a DC50 of 0.609 μM. This compound is applicable to breast cancer research.

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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