PROTAC PD-L1 degrader-1
Product Specifications
Target
PD-1/PD-L1, PROTACs
Related Pathways
PROTAC, Apoptosis, Immunology/Inflammation, Cell Cycle/Checkpoint
Bioactivity
PROTACPD-L1 degrader-1 is a CRBN-based PD-L1-PROTAC degrader with significant PD-L1 protein degradation capacity. It demonstrates strong PD-L1 degradation activity in 4T1 cells, with a DC50 of 0.609 μM. This compound is applicable to breast cancer research.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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SP-54841-1 1 mg
LEAP-2 (38 - 77) (Human) (AA: Met-Thr-Pro-Phe-Trp-Arg-Gly-Val-Ser-Leu-Arg-Pro-Ile-Gly-Ala-Ser-Cys-Arg-Asp-Asp-Ser-Glu-Cys-Ile-Thr-Arg-Leu-Cys-Arg-Lys-Arg-Arg-Cys-Ser-Leu-Ser-Val-Ala-Gln-Glu) (MW: 4585.36)
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