HDAC6-IN-43
Product Specifications
CAS Number
3037978-19-8
Target
HDAC
Related Pathways
DNA Damage/DNA Repair|||Chromatin/Epigenetic
Bioactivity
HDAC6-IN-43 (compound 26) is a potent inhibitor of HDACs. This compound effectively inhibits various HDACs, notably HDAC1, HDAC2, and HDAC6, with an IC50 of less than 150 nM, and demonstrates particularly high sensitivity to HDAC6 with an IC50 of 11 nM. HDAC6-IN-43 is utilized in the study of autosomal dominant polycystic kidney disease (ADPKD) .
Smiles
O=C(NO)CCCCCCOC1=CC(=CC=C1OC)C2=NC=3C=CC=CC3S2
Molecular Formula
C21H24N2O4S
Molecular Weight
400.49
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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