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HDAC6-IN-47

Product Specifications

Target

HDAC

Related Pathways

Chromatin/Epigenetic|||DNA Damage/DNA Repair

Bioactivity

HDAC6-IN-47 (Compound S-29b) is an HDAC inhibitor with high affinity for HDAC1, HDAC2, HDAC3, HDAC6, HDAC8, and HDAC10, with Ki values of 60, 56, 162, 0.44, 362, and 849 nM, respectively. It induces hyperacetylation of tubulin in MV4-11 cells and inhibits their proliferation with an EC50 of 0.50 µM. HDAC6-IN-47 is applicable in leukemia research.

Molecular Formula

C29H33N5O6

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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