Cantharidic acid
Product Specifications
CAS Number
28874-45-5
Target
Phosphatase, Apoptosis, p38 MAPK, JNK, ERK
Related Pathways
Apoptosis, MAPK, Metabolism
Bioactivity
Cantharidic acid is a selective inhibitor of protein phosphatase 2 (PP2A) and protein phosphatase 1 (PP1) . It impedes cell viability by upregulating the ERK1/2, p38, and JNK1/2 pathways, causes cell cycle arrest at the sub-G1 phase, and induces apoptosis in NPC-39 and HONE-1 cells.
Smiles
C(O)(=O)[C@@]1(C)[C@](C(O)=O)(C)[C@]2(O[C@@]1(CC2)[H])[H]
Molecular Formula
C10H14O5
Molecular Weight
214.22
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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