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MS181

Product Specifications

Target

E1/E2/E3 Enzyme, PROTACs

Related Pathways

PROTAC, Ubiquitination

Bioactivity

MS181 (compound 1) is an efficient PROTAC degrader that recruits cereblon (CRBN) and binds to the ubiquitin complex polycomb repressive complex 1 (PRC1) . It reduces the expression of EED, EZH2, SUZ12, BMI1, and RING1B, and exhibits antiproliferative activity.

Molecular Formula

C39H41N11O6

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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