MS181
Product Specifications
Target
E1/E2/E3 Enzyme|||PROTACs
Related Pathways
PROTAC|||Ubiquitination
Bioactivity
MS181 (compound 1) is an efficient PROTAC degrader that recruits cereblon (CRBN) and binds to the ubiquitin complex polycomb repressive complex 1 (PRC1) . It reduces the expression of EED, EZH2, SUZ12, BMI1, and RING1B, and exhibits antiproliferative activity.
Molecular Formula
C39H41N11O6
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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