PD-L1/CD-73-IN-1
Product Specifications
CAS Number
3048634-84-7
Target
CD73|||PD-1/PD-L1
Related Pathways
Cell Cycle/Checkpoint|||Apoptosis|||Immunology/Inflammation
Bioactivity
PD-L1/CD-73-IN-1 (compound CC-5) is an inhibitor of PD-L1 and CD73, with IC50 values of 6 nM and 0.773 ?M, respectively. It effectively inhibits tumor cell growth both in vitro and in vivo.
Smiles
N#CC1=CC=CC(=C1)COC2=CC(OCC3=CC=CC(C=4C=CC=CC4)=C3C)=C(Cl)C=C2CN5CCCCC5C(=O)N6CCN(C=7N=NC(=CC7)C8=CNC(=O)NC8=O)CC6
Molecular Formula
C47H45ClN8O5
Molecular Weight
837.36
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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