CA IX/VEGFR-2-IN-2
Product Specifications
Target
Carbonic Anhydrase, MDM-2/p53, Reactive Oxygen Species, Caspase, VEGFR, Bcl-2 Family, Cytochromes P450
Related Pathways
Metabolism, Apoptosis, NF-κB, Proteases/Proteasome, Immunology/Inflammation, Tyrosine Kinase/Adaptors, Angiogenesis
Bioactivity
CAIX/VEGFR-2-IN-2 (compound 5e) is a dual-target inhibitor with potent inhibitory effects on CAIX (KI=3.1 μM) and VEGFR-2 (IC50=32.1 nM) . This compound is applicable in research involving pancreatic cancer (PANC1), breast cancer (MCF7), and prostate cancer cells (PC3) .
Molecular Formula
C22H18FN3O3S
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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