GSK-3β/HDAC-IN-1
Product Specifications
Target
GSK-3, HDAC
Related Pathways
Chromatin/Epigenetic, Stem Cells, PI3K/Akt/mTOR signaling, DNA Damage/DNA Repair
Bioactivity
GSK-3β/HDAC-IN-1 (Compd 4) is a pioneering non-ATP competitive inhibitor that can penetrate the blood-brain barrier, targeting glycogen synthase kinase 3β/histone deacetylases (GSK-3β/HDACs) . It exhibits IC50 values of 0.142 μM for GSK-3β, 0.03 μM for HDAC2, and 0.045 μM for HDAC6. GSK-3β/HDAC-IN-1 is utilized in Alzheimer's research.
Molecular Formula
C20H15N3O4S
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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