VRK1/CK1-IN-1
Product Specifications
CAS Number
3050772-20-5
Target
Casein Kinase
Related Pathways
Metabolism, Stem Cells
Bioactivity
VRK1/CK1-IN-1 (compound 36) is a dual inhibitor targeting vaccinia-related kinase 1 (VRK1) and casein kinase 1 (CK1), with a Ki of 37.9 nM for VRK1. It exhibits IC50 values of 17 nM and 15 nM for CK1 δ and ε isoforms, respectively.
Smiles
C(N1C=2C(=NC(NC3=CC(F)=C(O)C(F)=C3)=NC2)N(C)[C@@H](C)C1=O)C=4ON=C(C)C4
Molecular Formula
C19H18F2N6O3
Molecular Weight
416.38
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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