LLC355
Product Specifications
Target
Discoidin Domain Receptor (DDR), ATTECs
Related Pathways
Tyrosine Kinase/Adaptors, PROTAC
Bioactivity
LLC355 is a discoidin domain receptor 1 (DDR1) ATTEC degrader. It efficiently degrades DDR1 protein, with a DC50 value of 150.8 nM in non-small cell lung cancer NCI-H23 cells. LLC355 induces DDR1 degradation via lysosome-mediated autophagy and effectively inhibits the tumorigenicity, migration, and invasion of cancer cells.
Molecular Formula
C63H64ClF3N10O5
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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