AR Degrader-1
Product Specifications
Target
Molecular Glues|||Androgen Receptor|||E1/E2/E3 Enzyme
Related Pathways
Endocrinology/Hormones|||Ubiquitination|||PROTAC
Bioactivity
AR Degrader-1 (Compound ML 2-9) is a monovalent degrader of androgen receptors (AR) categorized under molecular glues. In LNCaP prostate cancer cells, it facilitates AR degradation through DCAF16 (E3 ligase) while exhibiting minimal cytotoxicity.
Molecular Formula
C24H27ClN6O4S
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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