SOS1/EGFR-IN-1
Product Specifications
Target
EGFR|||Ras
Related Pathways
Tyrosine Kinase/Adaptors|||Angiogenesis|||MAPK|||JAK/STAT signaling
Bioactivity
SOS1/EGFR-IN-1 (compound SE-9) is a dual-target inhibitor for prostate cancer, effectively suppressing downstream effector molecules through the inhibition of SOS1 and EGFR. It induces apoptosis and G1 phase cell cycle arrest, reducing angiogenesis and migration. In prostate cancer cells PC-3, it demonstrates significant antitumor activity with an IC50 of 0.45±0.03 ?M.
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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