PRDX1-IN-2
Product Specifications
Target
Apoptosis, ROS Kinase
Related Pathways
Apoptosis, Tyrosine Kinase/Adaptors
Bioactivity
PRDX1-IN-2 (compound 15) is a selective inhibitor of the antioxidant enzyme Peroxiredoxin 1 (PRDX1) with an IC50 of 0.35 μM. It reduces mitochondrial membrane potential in SW620 cells, potentially due to increased ROS resulting from PRDX1 inhibition, leading to apoptosis. PRDX1-IN-2 is applicable in colorectal cancer research.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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