Probe-Cys

Probe-Cys is a water-soluble, selective near-infrared fluorescent probe for Cys (?ex= 680 nm, ?em=710 nm) that remains unaffected by Hcy, GSH, and HS-. This compound can react with the stimulant 1,4-dithiothreitol (DTT) and the inhibitor N-ethylmaleimide (NEM) in HepG2 cells and zebrafish for detecting endogenous Cys. Furthermore, Probe-Cys is applicable for imaging Cys in Arabidopsis thaliana. It offers a method for exploring cancer diagnostics and plant sulfur metabolism.