Pan-KRAS-IN-13
Product Specifications
CAS Number
3033637-76-9
Target
Ras
Related Pathways
MAPK
Bioactivity
Pan-KRAS-IN-13 (compound 2) is a potent inhibitor of KRAS, exhibiting IC50 values of 2.75 nM and 2.89 nM for its G12D and G12V mutations, respectively.
Smiles
FC1=C2C=3C(N4[C@@](CCOC3N=C1C=5C6=C(C=C(O)C5)C=CC(F)=C6C#C)(CNCC4)[H])=NC(OC[C@@]78N(C[C@H](F)C7)CCC8)=N2
Molecular Formula
C33H31F3N6O3
Molecular Weight
616.63
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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