What is the catalog number for NF-κB-IN-16?

The catalog number for NF-κB-IN-16 is T209749.

What sizes are available for NF-κB-IN-16?

NF-κB-IN-16 is available in the following size(s): 10 mg, 50 mg.

How many pack sizes does NF-κB-IN-16 come in?

NF-κB-IN-16 is available in 2 different pack sizes.

Is NF-κB-IN-16 in stock?

NF-κB-IN-16 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures NF-κB-IN-16?

NF-κB-IN-16 is manufactured by Molfinity.

What is the estimated delivery time for NF-κB-IN-16?

Estimated delivery time for NF-κB-IN-16 is approximately 10 business day(s), depending on your location.

NF-κB-IN-16

Product Specifications

Target

NF-κB, Apoptosis

Related Pathways

Apoptosis, NF-κB

Bioactivity

NF-κB-IN-16 (compound 9) is a complex of an NF-κB inhibitor and Cisplatin (Pt (IV) complex) with potent and low-toxicity antitumor activity. It can cause DNA damage, induce mitochondrial dysfunction, generate reactive oxygen species, and trigger apoptosis via mitochondrial pathways and endoplasmic reticulum stress. NF-κB-IN-16 effectively inhibits the NF-κB/MAPK signaling pathway and disrupts PI3K/AKT signal transduction. Additionally, it demonstrates excellent in vivo antitumor efficacy and low toxicity in A549 or A549/CDDP xenograft models.