IOX5
Product Specifications
Target
HIF/HIF Prolyl-Hydroxylase|||Apoptosis
Related Pathways
Chromatin/Epigenetic|||Apoptosis|||Metabolism
Bioactivity
IOX5 is a selective prolyl hydroxylase (PHD) inhibitor with an IC50 of 0.19 ?M for PHD2. In acute myeloid leukemia (AML) cells, IOX5 can stabilize HIF-1?, inhibit cell proliferation, and induce apoptosis. It exhibits anti-leukemia activity.
Molecular Formula
C17H19F3N4O2
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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