SIK-IN-3
Product Specifications
Target
AMPK
Related Pathways
Chromatin/Epigenetic, PI3K/Akt/mTOR signaling
Bioactivity
SIK-IN-3 (Compound 6B) is an inhibitor of salt-induced kinases (SIK), demonstrating inhibitory effects on SIK1, SIK2, and SIK3 with IC50 values of 0.1, 0.3, and 0.8 nM respectively. SIK-IN-1 inhibits TNFa release in human macrophages with an IC50 of 0.6 nM and stimulates LPS-induced IL-10 release with an EC50 of 3 nM.
Molecular Formula
C24H25N5OS
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS2803504-01 48 Tests
Rat Tyrosine-protein phosphatase non-receptor type substrate 1 (SIRPA) ELISA Kit
Sign In for Pricing
View Details MBS2803504-02 96 Tests
Rat Tyrosine-protein phosphatase non-receptor type substrate 1 (SIRPA) ELISA Kit
Sign In for Pricing
View Details MBS2803504-03 5x 96 Tests
Rat Tyrosine-protein phosphatase non-receptor type substrate 1 (SIRPA) ELISA Kit
Sign In for Pricing
View Details MBS2803504-04 10x 96 Tests
Rat Tyrosine-protein phosphatase non-receptor type substrate 1 (SIRPA) ELISA Kit
Sign In for Pricing
View Details GTR15386940 1 Vial
Lentiviral human HOXD13 sgRNA gene knockout kit - Lentiviral human HOXD13 sgRNA gene knockout kit (25)
Sign In for Pricing
View Details