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Glucocorticoid receptor/NF-κB modulator-1

Product Specifications

Target

Glucocorticoid Receptor, NF-κB

Related Pathways

Endocrinology/Hormones, NF-κB

Bioactivity

Glucocorticoid receptor/NF-κB modulator-1 (Compound 20) is a derivative of ocotillol. It prevents degradation of glucocorticoid receptor (GR) mRNA and GR protein and inhibits the activation of the NF-κB signaling pathway. Additionally, it reduces levels of nitric oxide (NO), interleukin (IL-6), and tumor necrosis factor-alpha (TNF-α), and improves sepsis in mice.

Molecular Formula

C39H62N2O6S

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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