Glucocorticoid receptor/NF-?B modulator-1
Product Specifications
Target
Glucocorticoid Receptor|||NF-?B
Related Pathways
Endocrinology/Hormones|||NF-?B
Bioactivity
Glucocorticoid receptor/NF-?B modulator-1 (Compound 20) is a derivative of ocotillol. It prevents degradation of glucocorticoid receptor (GR) mRNA and GR protein and inhibits the activation of the NF-?B signaling pathway. Additionally, it reduces levels of nitric oxide (NO), interleukin (IL-6), and tumor necrosis factor-alpha (TNF-?), and improves sepsis in mice.
Molecular Formula
C39H62N2O6S
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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