Glucocorticoid receptor/NF-κB modulator-1
Product Specifications
Target
Glucocorticoid Receptor, NF-κB
Related Pathways
Endocrinology/Hormones, NF-κB
Bioactivity
Glucocorticoid receptor/NF-κB modulator-1 (Compound 20) is a derivative of ocotillol. It prevents degradation of glucocorticoid receptor (GR) mRNA and GR protein and inhibits the activation of the NF-κB signaling pathway. Additionally, it reduces levels of nitric oxide (NO), interleukin (IL-6), and tumor necrosis factor-alpha (TNF-α), and improves sepsis in mice.
Molecular Formula
C39H62N2O6S
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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