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PAR4 antagonist 4

Product Specifications

CAS Number

3057206-41-1

Target

Protease-activated Receptor

Related Pathways

GPCR/G Protein

Bioactivity

PAR4 antagonist4 (Compound 37) is a selective antagonist of protease-activated receptor 4 (PAR4) . It exhibits antiplatelet activity with an IC50 of 14.2 nM. Moreover, PAR4 antagonist3 enhances metabolic stability in human liver microsomes, showing a half-life (T1/2) of 42.5 minutes.

Smiles

FC1=CC=C(OCC2OC=3C=CC=4C=C(OC4C3OC2)C=5N=C6SC(=NN6C5)OC)C=C1

Molecular Formula

C22H16FN3O5S

Molecular Weight

453.44

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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