PAR4 antagonist 3
Product Specifications
CAS Number
3057206-40-0
Target
Protease-activated Receptor
Related Pathways
GPCR/G Protein
Bioactivity
PAR4 antagonist3 (Compound 36) is a selective antagonist of protease-activated receptor 4 (PAR4) . It exhibits antiplatelet activity with an IC50 of 26.1 nM and enhances metabolic stability in human liver microsomes, with a half-life (T1/2) of 97.6 minutes.
Smiles
FC1=CC=C(OCC2OC3=C(OC2)C=CC=4C=C(OC34)C=5N=C6SC(=NN6C5)OC)C=C1
Molecular Formula
C22H16FN3O5S
Molecular Weight
453.44
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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