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Pan-KRAS-IN-10

Product Specifications

Target

Ras

Related Pathways

MAPK

Bioactivity

Pan-KRAS-IN-10 (Compound 58) acts as an inhibitor of the human tumor mutant gene KRAS. It suppresses the proliferation of KRAS mutant cells, specifically AsPC-1 (G12D mutant) and SW480 (G12V mutant), with IC50 values of 0.7 and 0.24 nM, respectively.

Molecular Formula

C45H57N7O5S

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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