Pan-KRAS-IN-10
Product Specifications
Target
Ras
Related Pathways
MAPK
Bioactivity
Pan-KRAS-IN-10 (Compound 58) acts as an inhibitor of the human tumor mutant gene KRAS. It suppresses the proliferation of KRAS mutant cells, specifically AsPC-1 (G12D mutant) and SW480 (G12V mutant), with IC50 values of 0.7 and 0.24 nM, respectively.
Molecular Formula
C45H57N7O5S
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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