Anti-osteoporosis agent-8
Product Specifications
Target
RANKL/RANK, NF-κB, p38 MAPK
Related Pathways
MAPK, NF-κB
Bioactivity
Anti-osteoporosis agent-8 (Compound 4aa) is a RANKL inhibitor, capable of preventing RANKL-induced osteoclastogenesis and osteoclast differentiation, with an IC50 of 2.41 μM. Furthermore, Anti-osteoporosis agent-8 has been shown to mitigate bone loss in an ovariectomized (OVX) mouse model.
Molecular Formula
C18H19F3N2O2Se
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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