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Anti-osteoporosis agent-8

Product Specifications

Target

RANKL/RANK|||NF-?B|||p38 MAPK

Related Pathways

MAPK|||NF-?B

Bioactivity

Anti-osteoporosis agent-8 (Compound 4aa) is a RANKL inhibitor, capable of preventing RANKL-induced osteoclastogenesis and osteoclast differentiation, with an IC50 of 2.41 ?M. Furthermore, Anti-osteoporosis agent-8 has been shown to mitigate bone loss in an ovariectomized (OVX) mouse model.

Molecular Formula

C18H19F3N2O2Se

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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